Tadao Akizawa Selected Research

maxacalcitol

3/2017	Research on kidney and mineral metabolism in Japan: past, present, and future.
6/2015	Comparison of paricalcitol with maxacalcitol injection in Japanese hemodialysis patients with secondary hyperparathyroidism.
5/2014	Active vitamin D analogs, maxacalcitol and alfacalcidol, as maintenance therapy for mild secondary hyperparathyroidism in hemodialysis patients - a randomized study.
11/2009	Improvement of impaired calcium and skeletal homeostasis in vitamin D receptor knockout mice by a high dose of calcitriol and maxacalcitol.
6/2008	Molecular and morphological approach of uremia-induced hyperplastic parathyroid gland following direct maxacalcitol injection.
1/2008	Direct injection of calcitriol or its analog improves abnormal gene expression in the hyperplastic parathyroid gland in uremia.
4/2007	Binding of highly concentrated maxacalcitol to the nuclear vitamin D receptors of parathyroid cells.
12/2004	Dose-response study of 22-oxacalcitriol in patients with secondary hyperparathyroidism.
9/2003	Percutaneous maxacalcitol injection therapy regresses hyperplasia of parathyroid and induces apoptosis in uremia.
6/2002	[Long-term clinical effect of maxacalcitol on hemodialysis patients with secondary hyperparathyroidism].

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Tadao Akizawa Research Topics

Disease

83	Chronic Renal Insufficiency 12/2022 - 10/2004
74	Secondary Hyperparathyroidism 06/2022 - 01/2002
63	Anemia 12/2022 - 04/2003
30	Hypoxia (Hypoxemia) 09/2022 - 01/2017
29	Chronic Kidney Failure (Chronic Renal Failure) 01/2021 - 01/2002
19	Cardiovascular Diseases (Cardiovascular Disease) 01/2019 - 01/2005
18	Hyperphosphatemia 07/2022 - 03/2003
14	Kidney Diseases (Kidney Disease) 01/2017 - 11/2003
10	Proteinuria 02/2021 - 01/2007
10	Inflammation (Inflammations) 01/2021 - 01/2009
10	Glomerulonephritis 01/2019 - 03/2003
8	Drug-Related Side Effects and Adverse Reactions 01/2022 - 01/2019
8	Diabetic Nephropathies (Diabetic Nephropathy) 06/2020 - 03/2003
7	Uremia 01/2021 - 09/2003
7	Hypercalcemia (Milk Alkali Syndrome) 01/2018 - 06/2002
7	Hyperplasia 08/2008 - 06/2003
6	Chronic Kidney Disease-Mineral and Bone Disorder (Renal Rickets) 11/2019 - 03/2003
6	Renal Insufficiency (Renal Failure) 08/2011 - 09/2005
5	Weight Gain 07/2021 - 01/2011
5	Vascular Calcification 01/2021 - 01/2008
5	Type 2 Diabetes Mellitus (MODY) 06/2020 - 11/2010
5	Bone Diseases (Bone Disease) 01/2018 - 03/2005
5	Hypertension (High Blood Pressure) 04/2014 - 04/2003
4	Neoplasms (Cancer) 12/2022 - 01/2010
4	Diabetes Mellitus 09/2022 - 01/2012
4	Vomiting 01/2021 - 01/2017
4	Atherosclerosis 01/2011 - 12/2004
4	Disease Progression 11/2010 - 12/2002
3	Diarrhea 02/2022 - 01/2021
3	Nausea 01/2021 - 06/2004
3	Peripheral Arterial Disease 01/2021 - 12/2002
3	Heart Failure 06/2020 - 01/2012
3	Infections 01/2019 - 08/2010
3	Stroke (Strokes) 12/2016 - 10/2007
3	Pruritus (Itching) 07/2014 - 12/2004
3	Acidosis 04/2014 - 12/2013
3	Hyperlipidemias (Hyperlipidemia) 09/2008 - 06/2004
2	COVID-19 05/2022 - 01/2021
2	Retinal Hemorrhage 04/2022 - 01/2020
2	Hypocalcemia 01/2022 - 03/2003
2	Iron Deficiencies 01/2021 - 01/2002

Drug/Important Bio-Agent (IBA)

29	CalciumIBA 02/2022 - 03/2003
27	Prolyl-Hydroxylase InhibitorsIBA 09/2022 - 01/2017
27	Hemoglobins (Hemoglobin)IBA 09/2022 - 03/2009
27	Parathyroid Hormone (Parathormone)IBA 06/2022 - 01/2002
26	HematinicsIBA 12/2021 - 06/2010
20	Erythropoietin FDA Link 08/2022 - 01/2002
20	Phosphates (Orthophosphate)IBA 02/2022 - 02/2005
18	Phosphorus (Red Phosphorus)IBA 02/2022 - 03/2003
18	Cinacalcet (Sensipar)FDA Link 01/2022 - 06/2004
18	MineralsIBA 10/2020 - 03/2005
16	Darbepoetin alfa (Aranesp)FDA Link 10/2021 - 02/2008
16	Vitamin D FDA LinkGeneric 01/2016 - 12/2002
13	IronIBA 08/2022 - 06/2010
13	evocalcetIBA 01/2022 - 01/2018
10	roxadustatIBA 09/2022 - 01/2019
10	molidustatIBA 04/2022 - 01/2019
10	maxacalcitolIBA 03/2017 - 06/2002
10	CreatinineIBA 04/2014 - 06/2004
9	Calcitriol Receptors (Calcitriol Receptor)IBA 01/2022 - 01/2005
7	Pharmaceutical PreparationsIBA 02/2022 - 02/2005
7	Serum AlbuminIBA 02/2019 - 01/2008
6	enarodustatIBA 08/2022 - 01/2019
6	etelcalcetide hydrochlorideIBA 01/2021 - 01/2017
6	bixalomerIBA 04/2017 - 12/2013
6	Calcitriol (Calcijex)FDA LinkGeneric 03/2017 - 06/2003
6	AST 120IBA 11/2010 - 03/2003
5	GSK1278863IBA 12/2022 - 01/2017
5	Ferritins (Ferritin)IBA 01/2021 - 01/2002
5	Therapeutic UsesIBA 01/2021 - 05/2009
5	Calcium-Sensing ReceptorsIBA 01/2018 - 10/2004
5	Sevelamer (RenaGel)FDA Link 01/2018 - 10/2003
5	Proteins (Proteins, Gene)FDA Link 06/2015 - 03/2003
5	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 01/2015 - 09/2005
4	tenapanorIBA 07/2022 - 01/2021
4	bardoxolone methylIBA 06/2020 - 01/2013
4	C-Reactive ProteinIBA 05/2020 - 01/2015
4	AlbuminsIBA 01/2019 - 07/2004
4	Biomarkers (Surrogate Marker)IBA 06/2018 - 06/2010
4	Ethanol (Ethyl Alcohol)IBA 08/2008 - 12/2002
3	Fibroblast Growth Factor-23IBA 01/2022 - 06/2010
3	Calcium Carbonate (Limestone)FDA Link 01/2021 - 03/2006
3	Prolyl Hydroxylases (Prolyl Hydroxylase)IBA 01/2021 - 11/2018
3	Dialysis SolutionsIBA 08/2020 - 01/2009
3	Antihypertensive Agents (Antihypertensives)IBA 07/2014 - 09/2005
3	Imatinib Mesylate (Gleevec)FDA Link 03/2013 - 05/2009
3	LipidsIBA 06/2010 - 08/2007
3	Antineutrophil Cytoplasmic Antibodies (ANCA)IBA 12/2009 - 10/2008
3	SterolsIBA 10/2008 - 06/2004
2	SodiumIBA 06/2022 - 09/2008
2	upacicalcetIBA 06/2022 - 01/2022
2	calcium phosphateIBA 11/2021 - 07/2009
2	Transferrin (beta 2 Transferrin)IBA 01/2021 - 07/2004
2	Alkaline PhosphataseIBA 01/2021 - 01/2009
2	lanthanum carbonate (Fosrenol)FDA Link 01/2021 - 02/2014

Therapy/Procedure

108	Renal Dialysis (Hemodialysis) 07/2022 - 04/2002
46	Therapeutics 01/2021 - 03/2003
7	Peritoneal Dialysis 04/2022 - 02/2008
5	Catheters 02/2011 - 01/2003
3	Parathyroidectomy 01/2019 - 08/2008